Renal, cardiovascular and metabolic effects of fetal programming
نویسندگان
چکیده
منابع مشابه
Renal, cardiovascular and metabolic effects of fetal programming.
Disturbed fetal development has long-lasting effects on the offspring, specifically a higher risk of renal, cardiovascular and metabolic disease in adult life as postulated by Barker’s hypothesis. Relevant to renal outcomes of the offspring are maternal factors such as pre-eclampsia, malnutrition, smoking, drugs etc. The main renal abnormalities in the offspring include reduced nephron number a...
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Adverse uterine environments experienced during fetal development can alter the projected growth pattern of various organs and systems of the body, leaving the offspring at an increased risk of metabolic disease. The thrifty phenotype hypothesis has been demonstrated as an alteration to the growth trajectory to improve the survival and reproductive fitness of the individual. However, when the i...
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The incidence of obesity and overweight has reached epidemic levels in the United States and developed countries worldwide. Even more alarming is the increasing prevalence of metabolic diseases in younger children and adolescents. Infants born to obese, overweight, and diabetic mothers (even when normal weight) have increased adiposity and are at increased risk of later metabolic disease. In ad...
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ژورنال
عنوان ژورنال: Nephrology Dialysis Transplantation
سال: 2012
ISSN: 0931-0509,1460-2385
DOI: 10.1093/ndt/gfs167